Microbiome Data Analytics for Biomarker Discovery

Competitive advantage

• Expertise in deep profiling of the human microbiome documented in high impact outputs
• Documented capacity to perform multi-omics strategies
• Long-term experience with the handling and extraction of a range of clinical samples

Impact

• Profiling the human microbiome – now causally linked to a range of diseases that fall within the broad themes of cancer, infectious disease, non-communicable diseases and mental health – using next generation sequencing and big data analytics.

Successful outcomes

• Identified microbial signatures associated with therapeutic efficacy of faecal microbiota transplantation in ulcerative colitis
• Identified novel associations between the oesophageal microbiome and the progression of the oesophageal adenocarcinoma cascade

Capabilities and facilities

• Experience in study design, patient recruitment and sample collection for optimal downstream analysis
• Handling and extraction of clinical samples of diverse origins
• Access to next-generation sequencing facilities and computing infrastructure to handle big data
• Established data analysis pipelines for signature discovery

Our partners

• Extensive list of clinical