Lab-on-a-Chip for the Medical Device Industry

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Lab-on-a-chip is a microdevice that controls chemical and biological processing using microfluidic integrated circuits. A laboratory process can be miniaturised, automated, and distributed to point-of-care. Alternatively, lab-on-a-chip can be automated and scaled-out using culture processes for delivery of cell and gene therapy.

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Competitive advantage

  • Integrating blood collection, separation, processing and analysis into plastic disposable devices
  • Lower cost of goods by reducing reagent consumption, laboratory infrastructure and skilled labour inputs
  • Internet connectivity

Impact

  • Increasing healthcare productivity through point-of-care diagnostics, early initiation of therapy, reduced cost-of-goods, and central coordination of resources and supply chains through the Internet-of-Things.

Successful outcomes

  • Invention, licensing, commercialisation and clinical translation of a hollow fibre bioreactor for closed automation of cell manufacture
  • Patent pending (US2017274196 (A1), 2014) on plastic microneedle patch for point-of-care blood diagnostics
  • Provisional filing on scaling microfluidics to manufacture cells for cell and gene therapy

Capabilities and facilities

  • Medical microdevice development from inception through to microfluidic design, fabrication, prototype evaluation, and clinical application

Our partners

  • Calimmune Australia Pty Ltd
  • CSL